Click here for the Department of Pathology & Laboratory Medicine Home Page Click here for the UC Irvine Home Page Click here for the School of Medicine Home Page
 
 
 
 

Critical Values for Infants (<12 Months)

Laboratory values in the critical range will be reported by telephone immediately.

On inpatients, the laboratory will attempt to phone the physician first; however, if the physician listed as the ordering physician is incorrect or does not respond within 10 minutes, the patient’s nurse will be notified.

Results will be reported only to a physician or nurse unless the location of the patient is in the recovery room, operating room, or labor and delivery and a physician or nurse cannot come to the phone.

Critical value laboratory test results will be phoned immediately to non-UC Irvine Pathology Referral Services clients. These results can be released to a clinical laboratory scientist at the referral client location when the ordering physician is unavailable.

The urgency of the contact will be emphasized to the individual accepting the phoned report, as well as the importance of contacting the appropriate physician.

Inability to contact the requesting physician, clinic, or office after two attempts will be followed up with an attempt to reach the pathology resident on call, the clinical pathology attending on call, or the director of the specific laboratory section in which the laboratory results occurred.

 

Test Critical Low Value Critical High Value 
Albumin  <2.0 g/dL  -----
ALT (SGPT)  -----  >100 IU/L
Ammonia  -----  >100 mcmol/L
Ammonia n nitrogen (arterial)  -----  >150 mcg/L
Bicarbonate  <14 mmol/L  >35 mmol/L
Bilirubin, direct  -----  >1.5 mg/dL
Bilirubin, micro:  -----  1 day: >6 mg/dL

 2 days: >10 mg/dL

 5 days-12 mos: >15 mg/dL
Bilirubin, total:  -----  >15 mg/dL
Blood culture  -----  Positive
Calcium, plasma  <6.5 mg/dL  >12 mg/dL
Calcium, ionized  <3.5 mg/dL  >6.0 mg/dL
Carbon dioxide (CO2)  <12 mM/L  -----
Chloride  <80 mEq/L  >117 mEq/L
Creatinine  -----  >2.0 mg/dL
Creatine phosphokinase (CPK)  -----  >1200 U/L
CSF, culture or gram stain  -----  Positive
Fibrinogen  <100mg/dL  -----
Gamma-glutamyltranspeptidase (GGT):  -----  >300 U/L
Glucose (blood):  <40 mg/dL  >200 mg/dL
Hematocrit  <21 %  >65 %
Hemoglobin  <7.0 gm/dL  >22.0 gm/dL
Lactate dehydrogenase (LDH)  -----  >3000 U/L
Lactic acid, plasma:  -----  >3.0 mmol/L
Magnesium (blood)  <1.2 mg/dL  >3.0 mg/dL
Nucleated cells (CSF)  -----

 

 > 5 cells present

 

Osmolality  -----

 

 > 300 mOsm/L

 

Base excess :

Neonates (arterial or capillary)

 <-10 mEq/L  -----
pH :  <7.25  >7.60
pCO2 :  -----  >75 mm Hg
pO2 :  <50 mm Hg  >100 mm Hg
Phosphorus

 

 <3 mg/dL

 

 >8 mg/dL
Platelet count  ≤50,000 /mm3  >1,000,000 /mm3
Prothrombin time (PT)  -----  >4.0 INR
Partial thromboplastin time (PTT)  -----  ≥80.0 sec
Potassium  <3.0 mEq/L  >6.0 mEq/L
Sodium  <125 mEq/dL  >150 mEq/dL
Transaminases (ALT or AST)  -----  >400 U/L
Urea Nitrogen (BUN)  -----  >60 mg/dL
Uric acid  -----  >12 mg/dL
WBC (blood)  ≤2,000 /mm3  ≥35,000 /mm3
% Bands  -----  >25 %
Therapeutic Drug Levels
Acetaminophen  -----  >150 mcg/mL
Amikacin  -----  Peak: >30.0 mcg/mL

 Trough: >10.0mcg/mL

Carbamazepine  -----  >15.0 mcg/mL
Cyclosporin  -----  >400 ng/mL
Digoxin  -----  >2.1 ng/mL
Dilantin  -----  >20.0 mcg/mL
Gentamicin  -----  Peak:  >12.0 mcg/mL

 Trough:  >2.0 mcg/mL

Lithium  -----  >1.5 mEq/L
Phenobarbital  -----  >50 mcg/mL
Salicylate  -----  >30 mg/mL
Sirolimus  -----

 >25 ng/mL: Liver Transplantation

 >15 ng/mL: Renal transplantation

Tacrolimus (FK506)  -----  >20 ng/mL
Theophylline  -----  >20.0 mcg/mL
Tobramycin  -----  Peak:  >12.0 mcg/mL

 Trough:  >2.0 mcg/mL

Valproic acid  -----  >120 mcg/mL
Vancomycin  ----- Peak: > 60.0 mcg/mL

Trough: <5.0 mcg/mL or >15.0 mcg/mL