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News & Events

2022

DateDescription
NOV 26Primary sinonasal lymphoma: A multi-institutional experience of clinical presentation, treatment, and outcomes
NOV 15Hypertrophic and fibrotic human PKD hearts are associated with macrophage infiltration and abnormal TGF-β1 signaling
OCT 22The Seventh Annual UCI Hematology Symposium
OCT 20Ensuring remote diagnostics for pathologists: an open letter to the US Congress
OCT 18UCI launches Center for Neurotherapeutics to facilitate drug discovery and therapy delivery
OCT 13Blood pressure variability and plasma Alzheimer's disease biomarkers in older adults
SEP 26UCI awarded $13.8 million federal contract to profile lipid nanoparticles
SEP 07Piezo1 regulates cholesterol biosynthesis to influence neural stem cell fate during brain development
SEP 02Multi-institutional review of sinonasal and skull base chondrosarcoma: 20-year experience
AUG 31Role of TRAIL-R in Primary and Secondary Genital and Respiratory Chlamydia muridarum Infections in Mice
AUG 23“Plasma exchange in a bottle”: An overview of efgartigimod for apheresis practitioners
AUG 09Discovery of compound that reactivate p53 mutants in vitro and in vivo
JUL 28Well-Differentiated Hypopharyngeal Liposarcoma-Associated Airway Obstruction
JUL 15Histone H2A ubiquitination resulting from Brap loss of function connects multiple aging hallmarks and accelerates neurodegeneration
JUL 12UCI research study links ALS to immune system dysfunction
JUN 22Clonally expanded CD8 T cells characterize amyotrophic lateral sclerosis-4
JUN 22Whole Genome Sequencing (WGS) for COVID-19 Outbreak Evaluations – How Much Does It Add to Bootstrap Epidemiology & Contact Tracing?
JUN 21PhD student receives National Science Foundation GRFP award
JUN 15Changes to HIV-1 RNA (Viral Load) by PCR, Quantitative Results
JUN 15Changes to Hepatitis B (HBV) DNA by PCR, Quantitative Result
MAY 31Chlorhexidine and Mupirocin for Clearance of Methicillin Resistant Staphylococcus aureus Colonization After Hospital Discharge: A Secondary Analysis of the CLEAR Trial
MAY 25Joint-label fusion brain atlases for dementia research in Down syndrome
MAY 22Commentary on Oeckl et al., "Serum Beta-Synuclein Is Higher in Down Syndrome and Precedes Rise of pTau181"
MAY 19A retrotransposon storm marks clinical phenoconversion to late-onset Alzheimer's disease
MAY 03Rare case of leptomeningeal small lymphocytic lymphoma with TP53 mutation detected by deep next-generation sequencing
MAY 02Experimental Pathology Research Conferences - RiP Talk with Chris Douglas
APR 25RESCHEDULED FOR FALL 2022: Experimental Pathology Research Conferences - Neil Theise
APR 20Updated Stability and Collection for Ammonia
APR 202022 NSF GRFP Recipient - Jacob Dohl
APR 19Beyond amyloid: Immune, cerebrovascular, and metabolic contributions to Alzheimer disease in people with Down syndrome
APR 18Change to Urinalysis (UA) Criteria with Reflex to Urine Culture
APR 11New Study From UCI Reveals How to Rejuvenate the Immune System of Elderly People and Reduce Their Risk of Infectious Disease
APR 11Experimental Pathology Research Conferences - RiP Talk with Jeremy Rouanet
APR 05Inter-species geographic signatures for tracing horizontal gene transfer and long-term persistence of carbapenem resistance
APR 04Association of Glyphosate Exposure with Blood DNA Methylation in a Cross-Sectional Study of Postmenopausal Women
APR 04Experimental Pathology Research Conferences - RiP Talk with Javi Lepe
MAR 23Conducting clinical trials in persons with Down syndrome: summary from the NIH INCLUDE Down syndrome clinical trials readiness working group
MAR 18Age-associated impairment of T cell immunity is linked to sex-dimorphic elevation of N-glycan branching
MAR 16Cell-free Scaled Production and Adjuvant Addition to a Recombinant Major Outer Membrane Protein from Chlamydia muridarum for Vaccine Development
MAR 14Experimental Pathology Research Conferences - Kojo Elenitoba-Johnson
MAR 01Prognostic value of O6-methylguanine-DNA methyltransferase methylation in isocitrate dehydrogenase mutant gliomas
FEB 24Probing the proteome to explore potential correlates of increased Alzheimer's-related cerebrovascular disease in adults with Down syndrome
FEB 23Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures
FEB 23Microglia Do Not Restrict SARS-CoV-2 Replication following Infection of the Central Nervous System of K18-Human ACE2 Transgenic Mice
FEB 02A novel nonsense variant in the NFE2L1 transcription factor in a patient with developmental delay, hypotonia, genital anomalies and failure to thrive
JAN 25Got Blood? Donate this week!
JAN 20Pediatric coccidioidal orbital granuloma
JAN 04Selective Impairment of Long-Range Default Mode Network Functional Connectivity as a Biomarker for Preclinical Alzheimer’s Disease in People with Down Syndrome
JAN 01Oral estrogen leads to falsely low concentrations of estradiol in a common immunoassay

2021

DateDescription
DEC 31CAA and related co-morbidities in Down syndrome and Alzheimer disease
DEC 18Mammography screening and mortality by risk status in the California teachers study
DEC 18De novo pathogenic variant in SETX causes a rapidly progressive neurodegenerative disorder of early childhood-onset with severe axonal polyneuropathy
DEC 17Expression of Endogenous Retroviral RNA in Prostate Tumors has Prognostic Value and Shows Differences among Americans of African Versus European/Middle Eastern Ancestry
DEC 045. The PROTECT Trial: A Cluster Randomized Clinical Trial of Universal Decolonization with Chlorhexidine and Nasal Povidone Iodine Versus Standard of Care for Prevention of Infections and Hospital Readmissions among Nursing Home Residents
NOV 30UCI-led study confirms linkage between altered DNA repair and DNA damage in neurodegenerative conditions causing debilitating movement disorders
NOV 30Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7
NOV 24A Survey of Preclinical Studies Evaluating Nanoparticle-Based Vaccines Against Non-Viral Sexually Transmitted Infections
NOV 23Anti-streptolysin O Titer (ASO) Test Discontinuation
NOV 22Infection Prevention Strategies in COVID-19 Units Highly Protective While Primary Risks to Healthcare Professionals Come from Co-workers and the Community
NOV 22New Laboratory Test Directory Website
NOV 19Disruption of beta-catenin dependent Wnt signaling in colon cancer cells remodels the microenvironment to promote tumor invasion
NOV 16Identifying dementia in Down syndrome with the Severe Impairment Battery, Brief Praxis Test and Dementia Scale for People with Learning Disabilities
OCT 25Blood Drive - 10th Anniversary Celebration
OCT 14Discontinuation of certain specialty tests
OCT 14Primitive Reflexes and Dementia in Adults With Down Syndrome
OCT 14Aggressive CD5-Postitive Primary Bone Marrow Diffuse Large B-Cell Lymphoma with Leukemic Presentation
OCT 6Changes to Heparin Therapeutic Range (aPTT Target) Oct. 2021
SEP 13Replacement Test: Cytochrome P450-2C19 (CYP2C19) Nucleic Acid Detection Tests
AUG 22Cognitive and Behavioral Domains That Reliably Differentiate Normal Aging and Dementia in Down Syndrome
AUG 20Diagnostic and prognostic performance and longitudinal changes in plasma neurofilament light chain concentrations in adults with Down syndrome: a cohort study
AUG 13Postmortem Neocortical 3H-PiB Binding and Levels of Unmodified and Pyroglutamte AB in Down Syndrome and Sporadic Alzheimer's Disease
AUG 09PAN-HEME NGS Panel
AUG 01Mandibular Chondrosarcoma Reconstructed Using Custom Implant and Radial Forearm Free Flap
JUL 31Too lean: Time to build back true resiliency in the national blood supply
JUL 20Respiratory dysfunction in a mouse model of spinocerebellar ataxia type 7
JUL 19RNA expression difference in prostate tumors and tumor-adjacent stroma between Black and White Americans
JUL 14SUMOylated Senataxin functions in genome stability, RNA degradation, and stress granule disassembly, and is linked with inherited ataxia and motor neuron disease
JUL 13Changes to Hepatitis C (HCV) RNA by PCR Quantitative Result
JUL 09New Test: Rapid Molecular Panel on Positive Blood Culture
JUL 08Single-nucleus chromatin accessibility and transcriptomic characterization of Alzheimer's disease
JUL 08The Lines that Held Us: Assessing Racial and Socioeconomic Disparities in SARS-CoV-2 Testing
JUL 07Induction of Protection in Mice against a Chlaymdia muridarum Respiratory Challenge by a Vaccine Formulated with the Major Outer Membrane Protein in Nanolipoprotein Particles
JUL 06APOE e4 Association with Cognition and Alzheimer Disease Biomarkers in Down Syndrome--Implications for Clinical Trials and Treatments for All
JUN 14Charcot-Bouchard aneurysms revisited: clinicopathologic correlations
JUN 11Association of mammographic density with blood DNA methylation
JUN 10The Arnold P. Gold Foundation recogizes UCI Champions of Humanistic Care at 2021 Gala
JUN 08Update: Removal of Race Labels on Calculated eGFR
MAY 26Lactate Dehydrogenase Reference Interval Update
MAY 25Special Blood Drive - UCIMC Pavilion 3
MAY 11In-N-Out Blood Drive - Irvine Campus
MAY 05New Test: Lipid Panel with Reflex to Direct LDL
MAY 05Method Update for Ceruloplasmin, C3 and C4
APR 30The Deubiquitainating Enzyme USP7 Regulates the Transcription Factor Nrf1 by Modulating its Stability in Response to Toxic Metal Exposure
APR 28Cross-Sectional Exploration of Plasma Biomarkers of Alzheimer's Disease in Down Syndrome: Early Data from the Longitudinal Investigation for Enhancing Down Syndrome Research (LIFE-DSR) Study
APR 28Genome-Wide B Cell, CD4+, and CD8+ T Cell Epitopes that are HIghly Conserved Between Human and Animal Coronaviruses, Identified from SARS-CoV2 as Targets for Preemptive Pan-Coronavirus Vaccines
APR 26New Test: Hepatitis B Virus E Antigen (HBeA) and Antibodies (anti-HBe)
APR 22A Primary Chlamydia trachomatis Genital Infection of Rhesus Macaques Identifies New Immunodominant B-cell Antigens
APR 15Opportunities, barriers, and recommendations in down syndrome research
APR 14NPM1 Mutation Analysis
APR 07New Test: Lipoprotein(a) and Direct LDL-C
MAR 29Special Three-Day Blood Drive
MAR 20Factors Associated with Women's Unwillingness to Decrease Alcohol Intake to Decrease Breast Cancer Risk
MAR 17Taxonomic Changes and Terminology Update of Clinically Significant Bacteria
MAR 08Chlamydia trachomatis vaccines for genital infections: where are we and how far is there to go?
FEB 15Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture
FEB 12The use of therapeutic plasma exchange as adjunctive therapy in the treatment of coronavirus disease 2019: A critical appraisal of the current evidence
FEB 12Age- and Sex-Associated Variations in the Sensitivity of Seriological Tests Among Individuals Infected with SARS-CoV-2
FEB 04Changes to Heparin Therapeutic Range (aPTT Target) 2021
JAN 30Longitudinal analyses reveal age-specific immune correlates of COVID-19 severity
JAN 26Change in Sendout Lab for Certain Infectious Disease Molecular Tests
JAN 26Albert La Spada named new associate dean of research development
JAN 19In vivo assessment of neurodegenerative in Spinocerebellar Ataxia type 7
JAN 19Human Neural Stem Cells Differentiate and Inegrate Innervating Implanted zQ175 Huntington's Disease Mouse Striatum

2020

DateDescription
DEC 23i-STAT Cartridge Storage May Result in Erroneously High Ionized Calcium
DEC 22Transcriptome Analysis of Ovarian and Uterine Clear Cell Malignancies
DEC 16Plasma Total-Tau and Neurofilament Light Chain as Diagnostic Biomarkers of Alzheimer's Disease Dementia and Mild Cognitive Impairments in Adults with Down Syndrome
DEC 02UCI Health Blood Drive - UCI Campus Parking Lot# 5
NOV 26A Patient in Need of a Red Cell Exchange?
NOV 24New Test: Respiratory Pathogen Nucleic Acid Detection Panel
NOV 14Longitudianl assessment of dementia measures in Down syndrome
NOV 03New In-house Test: Access Interleukin 6
NOV 02Irvine Blood Dive - Urgent Need
OCT 27New Test: Coronavirus 2019 (COVID-19) Nucleic Acid Detection Tests
OCT 27The AT(N) framework for Alzheimer's disease in adults with Down syndrome
OCT 142019 ARIISE AWARDS - Nominees & Finalists
OCT 14Advancing breakthrough science
OCT 12Free COVID-19 Antibody Test
OCT 01Vaccination with the recombinant major outer membrane protein elicits long-term protection in mice against vaginal shedding and infertility following a Chlamydia muridarium genital challenge
OCT 01Automated leukocyte parameters are useful in th eassessment of myelodysplastic syndromes
SEP 30A preliminary study of cerebral flood flow, aging and dementia in people with Down syndrome
SEP 28Mandibular Chondrosarcoma Reconstructed Using Custom Implant and Radial Forearm Free Flap
SEP 18Alzheimer's-related cerebrovascular disease in Down syndrome
SEP 18Induction of protection in mice against a respiratory challenge by a vaccine formulated with exosomes isolated from Chlamydia muridarum infected cells
SEP 02Updated SARS-CoV-2 IgG Serology Testing
AUG 15Abstract 1558: RNA Expression Differences Between African Americans and European Americans Prostate Cancers in Both their Tumor-Adjacent Stroma and in their Tumors
JUL 31Free COVID-19 Antibody Testing
JUL 27Revving up research
JUL 24Increase in COVID-19 testing capacity - Molecular Diagnostic Lab go live
JUL 22Update to Glucose Critical Value
JUL 15University Hills / UCI Health Blood Drives
JUL 13UC Irvine awarded $14.4 million Alzheimer's research grant
JUL 08Donate Blood and Win a Puck from the Ducks!
JUN 30Proteomic profiles for Alzheimer's disease and mild cognitive impairment among adults with Down syndrome spanning serum and plasma: An Alzheimer's Biomarker Consortium-Down Syndrome (ABC-DS) Study
JUN 27Biomarkers in Down syndrome can help us understand Alzheimer's disease
JUN 22HIgh Prevalence of Multidrug-Resistant Organism Colonization in 28 Nursing Homes: An "Iceberg Effect"
JUN 18Could I have immunity to the COVID-19 virus?
JUN 16Changes to Heparin Therapeutic Range (aPTT Target)
JUN 15Whole Blood Lead Reference Interval Update
JUN 12APOE Genotype-Dependent Pharmacogenetic Responses to Rapamycin for Preventing Alzheimer's Disease
JUN 09Myeloid 75-Gene Mutation Panel by Next Generation Sequencing
JUN 08Robert Edwards receives the Silver Beaker Award for Excellence in Teaching
JUN 05Transfusion Transmitted Babesiosis: A Systematic Review of Reported Cases
JUN 05Diversion of prime to ameliorate citrate toxicity in pediatric extracorporeal apheresis
MAY 27UCI Podcast: The race for COVID testing with Dr. Ed Monuki
MAY 08Protection against a chlaymdial respiratory challenge by a chimeric vaccine formulated with the Chlamydia muridarium major outer membrane protein variable domains using the Neisseria lactamica porin B as a scaffold
MAY 07UC Irvine COVID-19 Research Biobank - Accepting Applications
APR 30Improved protection against Chlamydia muridarum using native major outer membrane protein trapped in Resiquimod-carrying amphipols and effects in protection with addition of a Th1 and a Th2 adjuvant
APR 27Update: SARS-CoV-2 IgG Antibody Testing
APR 25First Reported Case of Extramedullary Plasmacytoma of the Appendix
APR 22New Test Offering: SARS-CoV-2 IgG Antibody Testing
APR 21Intact Parathyroid Hormone Method Update
APR 20How a Tumor Gets its Spots
APR 15Brain insulin resistance triggers early onset Alzheimer disease in Down syndrome
APR 10Coronavirus 2019 (COVID-19) Nucleic Acid Detection Tests - Update
APR 7Enumeration of Ampicillin-resistant E. Coli in Blood Using Droplet Microfluids and High-Speed Image Processing
APR 01Primary non-Hodgkin lymphoma of the tongue base: the clinicopathology of seven cases and evaluation of HPV and EBV status
MAR 27Coronavirus 2019 (COVID-19) Nucleic Acid Detection Tests
MAR 25Immune response against Chlamydia trachomatis via toll-like receptors is negatively regulated by SIGIRR
MAR 19UCI Blood Donor Center Donation Request
MAR 19Service Brief on COVID-19 (SARS-CoV2) and the Blood Supply
MAR 14High-grade B-cell Lymphoma with MYC and BCL2 Rearrangement Arising from Follicular Lymphoma: Presentation as a Large Peripancreatic Mass
MAR 02Protection of outbred mice against a vaginal challenge by a Chlamydia trachomatis serovar E recombinant major outer membrane protein vaccine is dependent on phosphate substitution in the adjuvant
FEB 07Rapid bacterial detection and antibiotic susceptibility testing in whole blood using one-step, high throughput blood digital PCR
JAN 24Enterovirus by PCR (CSF): In-house Test Discontinuation
JAN 17Urgent Recall Memo: iSTAT CHEM8+ Recall Notification
JAN 10Congratuations! Jasmine Huang - Staff Recognition Award Recipient
JAN 08Anaplastic thyroid carcinoma histologically mimicking a plasmacytoma
JAN 04Epstein-Barr virus association with plasma cell neoplasms
JAN 01A Recombinant Chlamydia trachomatis MOMP Vaccine Elicits Cross-serogroup Prorection in Mice Against Vaginal Shedding and Infertility

2019

DateDescription
DEC 09A Phase IIa Trial of Metformin for Colorectal Cancer Risk Reduction among Individuals with History of Colorectal Adenomas and Elevated Body Mass Index
NOV 28National Institute of Allergy and Infectious Diseases workshop report: "Chlamydia vaccines: The way forward"
NOV 27T-cell, B-cell, and NK-Cell Reference Range Changes
NOV 22New Test: High Sensitivity Troponin I
NOV 19Characterization of the Horizontal and Vertical Sexual Transmission of Chlamydia Genital Infections in a New Mouse Model
NOV 13Unit Measurement Change for IgG Subclasses 1, 2, 3, 4
NOV 12The Use of Optical Coherence Tomography and Convolutional Neural Networks to Distinguish Normal and Abnormal Oral Mucosa
OCT 25Measles Update: Measles IgG New Cut-off
OCT 24NIH establishes Cooperative Research Center with Lawrence Livermore National Laboratory and two University of California campuses, Irvine and Davis
OCT 23The SHIELD Orange County Project: A Decolonization Strategy in 35 Hospitals and Nursing Homes Reduces Multi-Drug-Resistant Organism (MDRO) Prevalence in a Southern California Region
OCT 19Granuloma-like lesion at subcutaneous immunoglobulin site in a common variable immunodeficiency patient
OCT 15The SHIELD Orange County Project: Multidrug-resistant Organism Prevalence in 21 Nursing Homes and Long-term Acute Care Facilities in Southern California
OCT 14Direct Oral Anticoagulant (DOAC) Reversal: Andexxa Versus 4 Factor Prothrombin Concentrates
OCT 022 Ducks Tickets + 2 Hats - Donate Blood Wednesday, Oct. 2
OCT 01Pleural Fluid pH Testing Updated Location and Test Code
SEP 24New Test: Hepatitis B Surface Antibody, Qualitative & Quantitative
SEP 10Understanding Frailty and Its Correlation with Treatment Choices and Outcomes in Older Adults with DLBCL: Single Center Experience with FIL Tool
AUG 26New Test Update: Sensitive Estradiol Immunoassay
AUG 21Blood Donor-Recipient Sex Mismatch: Outcomes Impacted?
AUG 21New Test: Rotem Viscoelastic Test
AUG 19Prolymphocytic transformation of lymphoplasmacytic lymphoma: an extremely unusual event
JUL 31Removal of Blood Urea Nitrogen (BUN) from Critical Values List
JUL 03Transcending gender: recognizing the impact of gender identity on blood collection
JUN 30Hyams grading as a predictor of metastasis and overall survival in esthesioneuroblastoma: a meta-analysis
JUN 15Crucial role for pathology residents in laboratory self-inspection, a single Institute's experience
JUN 05Immune-stimulatory gene expression in stroma cells of African-American postate cancer tissues
MAY 24Congratulations to Rob Edwards - Excellence in Teaching and Dean's Scholar Awards
MAY 23Solving the Mystery of a Coagulopathy Outbreak
MAY 21Sepsis and Lactic Acid, Plasma Normal Range
MAY 14IKKbeta Slows Huntington's Disease Progression in R6/1 Mice
APR 19New Test: Lipid Panel, Non-Fasting (LIPSC2)
APR 09Nicotine Acts on Cholinergic Signaling Mechanisms to Directly Modulate Choroid Plexus Function
APR 01Epstein-Barr Virus Incidental Expression in Bone Marrow Cells: A Study of 230 Consecutive Bone Marrow Biopsy Samples
MAR 13Method Update for Serum Free Light Chains, IgG Subclasses, Immunoglobulins IgG, IgA, and IgM
FEB 25Nonbinary gender or unknown sex and laboratory reference ranges update
FEB 14Decolonization to Reduce Postdischarge Infection Risk among MRSA Carriers
JAN 30UCI Pathologist Named 2019 Physicians of Excellence
JAN 14Changes to BK Virus DNA by PCR, Quantitative Testing
JAN 2Nonbinary or unknown gender and laboratory reference ranges

2018

DateDescription
DEC 21Changes to cytomegalovirus (CMV) DNA by PCR, quantitative testing
NOV 16Delivery on ice no longer required for lactic acid, plasma collected in grey-top tubes
NOV 08Notice of Test Menu Changes
OCT 12Delay in 2C19 Results
SEP 18New Test for BCR-ABL1 Minor (p190), Quantitative
SEP 07Delay in Mycobacteria Results
JUL 25AML, 10-Gene Panel Next Generation Sequencing
JUL 20Removal of temperature correction for blood gas analysis: pH, pCO2, pO2
JUL 13New electronic Interface with Mayo Medical Laboratories
JUN 29HLA, T & B cell crossmatch by flow cytometry (kidney and/or pancreas pre-transplant)
JUN 21New Test: Herpes Simplex Virus Type 1 & 2 by real-time Polymerase Chain Reaction (PCR)
MAY 21New Tests: Testosterone Free, Adult Male; Sex Hormone Binding Globulin
APR 25BCR-ABL1 P210 IVD Quantititative qPCR Test
APR 16Date Correction: Change in Lab Methodology for D-Dimer Testing
APR 06Change in Lab Methodology for D-Dimer Testing
MAR 16Faxitron PathVision System
MAR 13Ellena Peterson, professor of pathology, and Terrance Mayes, associate vice chancellor for diversity and inclusion awarded UCI Confronting Extremism Initiative
MAR 07Congratulations to our 2017 ARIISE Award Nominees and Finalists from Pathology
MAR 02Elimination of thymoglobulin depletion in serum samples for testing anti-HLA antibodies.
MAR 01We are seeking qualified candiates for all ranks in the non-tenured track Health Sciences Clinical Professor Series, expertise in GI/Liver pathology desired.
FEB 26Procalcitonin Testing (PCT) will be performed in the Microbiology Division.
FEB 23New Test: FLT3 mutation, PCR (FLT3-ITD; FLT3-D835)
FEB 06Dedicated Collection Tubes for Microbiology Molecular Testing
FEB 05New Access TSH (3rd IS) Assay
JAN 22Register now for the 3rd Annual UC Irvine Health Hematology Symposium, which will be held Saturday, April 21, 2018.
JAN 08Dr. Farah Rahmatpanah receives the American Cancer Society Seed Grant to fund her prostate cancer research